Among several potential transmission sources in the spreading of the COVID-19, dental services have received a high volume of attention. The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer. 2 2020;8(4):128. The number of people suffering from inflammatory bowel diseases, especially Crohn's disease, has increased remarkably. Aassve A, Cavalli N, Mencarini L, Plach S, Livi BM. 1093/gerona/glaa099. Objective In March 2020, several countries banned unnecessary outdoor activities during COVID-19, commonly called ‘lockdowns. In patients with intracerebral hemorrhage (ICH), circulating myeloid cells increase and peripheral immune cells infiltrate into the brain parenchyma. This suggests that a key contributory factor could be immunosenescence that is both age-related and lifestyle-induced. The COVID-19 pandemic and human fertility. Google Scholar doi:10.1007/ s11596-020-2172-6 This is a retrospective case series of 25 children <14 years of age hospitalised with COVID-19 from 10 hospitals across the Hubei province between February 1st and February 10th 2020. The mechanisms mediating the increased production of monocytes and their influence on ICH remain to be elucidated. Biologics are large molecule therapeutics that do not cross the blood-brain barrier (BBB). Aiming to contain the spread of the virus, leaders of many countries restrained social movement, targeting to flatten the curve of contamination with social distancing. Due to its fast dissemination, the World Health Organization declared a pandemic in March 2020. Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H. et al. 2 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 ... Impact factor 3.193. Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis. Eur J Sport Sci. Citescore 6.3. Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. By 7 May, 3.67 million had tested positive and more than 250 000 had died. Crohn's disease is assumed to be the result of a complex interplay between genetic susceptibility, … Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H. et al. ... Sci Transl Med, 8 (2016), p. 343ra82. Cancer Treat Rev 2016 ;45: 139 - 162 . The emergence of SARS-CoV-2 in December 2019 prompted consternation in many parts of the world. Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Zhang L, Liu Y. Strategies to decrease low-density lipoprotein (LDL) cholesterol could help treat atherosclerosis. CAS PubMed PubMed Central Google Scholar 91. Among several potential transmission sources in the spreading of the COVID-19, dental services have received a high volume of attention. 2020;8(4):128. Yoon SH, Kang JM, Ahn JG. Immune effector cell (IEC) therapies offer durable and sustained remissions in significant numbers of patients with hematological cancers. Strategies to decrease low-density lipoprotein (LDL) cholesterol could help treat atherosclerosis. S N A M Razali 1, M S Rusiman 1, W S Gan 1 and N Arbin 2. Zhang L, Liu Y. Several reports, papers, guidelines, and suggestions have been released on how this infection could be transmitted through dental services and what should be done. The 50-item International Personality Item Pool was used to assess personality traits according to the five-factor model of personality. (2020) Impact of COVID-19 on lifestyle-related behaviours-a cross-sectional audit of responses from nine hundred and ninety-five participants from India. Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 ... Impact factor 3.193. By 7 May, 3.67 million had tested positive and more than 250 000 had died. 2020;117(19):10484–91. 2 It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. 2017:9 22. developed an antisense oligonucleotide (ASO) that can be delivered orally, is taken up by the liver, and targets PCSK9, which regulates the LDL receptor.Subcutaneous administration of the ASO showed high potency in mice overexpressing … Curr Med Sci 2020;:1–6. The mechanisms mediating the increased production of monocytes and their influence on ICH remain to be elucidated. Proc Natl Acad Sci U S A. Zhang L, Liu Y. 2020;117(19):10484–91. By 10 March 2020, 4296 persons world-wide had died from COVID-19 infection. Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. From 1890 to today, how the field of immunotherapy has progressed from theory to scientific research to clinical trials to cutting-edge cancer treatment with the support of the Cancer Research Institute (CRI), including milestones, discoveries, technologies, and treatments. This suggests that a key contributory factor could be immunosenescence that is both age-related and lifestyle-induced. Eur Rev Med Pharmacol Sci. Citescore 6.3. Clinical outcomes of 201 neonates born to mothers with COVID-19: a systematic review. By 10 March 2020, 4296 persons world-wide had died from COVID-19 infection. CAS PubMed PubMed Central Article Google Scholar 9. Immune effector cell (IEC) therapies offer durable and sustained remissions in significant numbers of patients with hematological cancers. ... Ranjan, P, Singh, V et al. Yang S, Cao P, Du P, Wu Z, Zhuang Z, Yang L, et al. Cancer Treat Rev 2016 ;45: 139 - 162 . Yang S, Cao P, Du P, Wu Z, Zhuang Z, Yang L, et al. The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer. Proc Natl Acad Sci U S A. BBB drug delivery is the limiting factor in the future development of new therapeutics for the brain. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. 1 IntroductionAs of 30th January 2020, the outbreak of the novel coronavirus disease, latterly called COVID-19, was declared a Public Health Emergency (World Health Organization, 2020b) and on the 11th of March 2020, COVID-19 was characterized as a pandemic (World Health Organization, 2020d). Strategies to decrease low-density lipoprotein (LDL) cholesterol could help treat atherosclerosis. It also protects the body from harmful substances, germs, and cell changes (neoplasm) [].The key player in the immune system is the white blood cells, which can travel throughout the body through the blood vessels. Alzheimer’s disease (AD) and treatment of the brain in aging require the development of new biologic drugs, such as recombinant proteins or gene therapies. 2020;110(11):1081–5. CAS PubMed PubMed Central Article Google Scholar 9. Sci Transl Med. The 50-item International Personality Item Pool was used to assess personality traits according to the five-factor model of personality. doi:10.1007/ s11596-020-2172-6 This is a retrospective case series of 25 children <14 years of age hospitalised with COVID-19 from 10 hospitals across the Hubei province between February 1st and February 10th 2020. Brasil Rev Assoc Med Bras. In this review, we critically appraise the current pharmacological, preclinical and clinical data of azithromycin for treating COVID-19. Crohn's disease is assumed to be the result of a complex interplay between genetic susceptibility, … Potential Interventions for Novel Coronavirus in China: A Systemic Review. Potential Interventions for Novel Coronavirus in China: A Systemic Review. First Case of 2019 Novel Coronavirus in the United States. ... Sci Transl Med, 8 (2016), p. 343ra82. Eur Rev Med Pharmacol Sci. J Med Virol. Due to its fast dissemination, the World Health Organization declared a pandemic in March 2020. (2020) Impact of COVID-19 on lifestyle-related behaviours-a cross-sectional audit of responses from nine hundred and ninety-five participants from India. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. 2020;24(14):7804–15. This suggests that a key contributory factor could be immunosenescence that is both age-related and lifestyle-induced. The body contains the organs of the immune system (), which protects against diseases [9,10].It plays a key role to maintain health and pathogenesis. These lockdowns have the potential to impact associated levels of physical activity and sedentary behaviour. Narici M., De Vito G., Franchi M., Paoli A., Moro T., Marcolin G. Impact of sedentarism due to the COVID-19 home confinement on neuromuscular, cardiovascular and metabolic health: physiological and pathophysiological implications and recommendations for physical and nutritional countermeasures. Ann Transl Med. In contrast, SCI is typically triggered by DAMPs in the absence of an acute infectious insult or activation of PAMPs 30,31,32.SCI often increases with … COVID-19 has been declared as pandemic by World Health Organization (WHO) in March 11, 2020 and till June 25, 2020 confirmed infections are 9,110,186 with 473,061 deaths across 216 countries . 2020 23. More Information. Here, Shi et al. Google Scholar 2020 23. Here, Gennemark et al. The emergence of SARS-CoV-2 in December 2019 prompted consternation in many parts of the world. Yoon SH, Kang JM, Ahn JG. If patients with COPD are asked to shield, it is important that they are given advice about keeping active and exercising as much as possible while shielded. 2017:9 22. Objective In March 2020, several countries banned unnecessary outdoor activities during COVID-19, commonly called ‘lockdowns. Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 ... Impact factor 3.193. The emergence of SARS-CoV-2 in December 2019 prompted consternation in many parts of the world. BBB drug delivery is the limiting factor in the future development of new therapeutics for the brain. CAS PubMed PubMed Central Article Google Scholar 9. Narici M., De Vito G., Franchi M., Paoli A., Moro T., Marcolin G. Impact of sedentarism due to the COVID-19 home confinement on neuromuscular, cardiovascular and metabolic health: physiological and pathophysiological implications and recommendations for physical and nutritional countermeasures. Google Scholar 84. Brasil Rev Assoc Med Bras. showed that bone marrow hematopoietic stem cells (HSCs) increased in patients with ICH and in a mouse model. Modeling suggests shielding is an effective strategy to protect individuals and control the impact of SARS-CoV-2 . 2020;110(11):1081–5. Eur J Sport Sci. COVID-19 has been declared as pandemic by World Health Organization (WHO) in March 11, 2020 and till June 25, 2020 confirmed infections are 9,110,186 with 473,061 deaths across 216 countries . S Afr Med J. Ann Transl Med. More Information. First Case of 2019 Novel Coronavirus in the United States. N Engl J Med. Crohn's disease is assumed to be the result of a complex interplay between genetic susceptibility, … Fernandes do Nascimento JS, RRT C, Fernandes do Nascimento JK, Knoploch BB, PMCO D, MAO N. Coinfection of SARS-CoV-2 and measles morbillivirus in a front-line health worker in Rio de Janeiro. Crossref In patients with intracerebral hemorrhage (ICH), circulating myeloid cells increase and peripheral immune cells infiltrate into the brain parenchyma. The factor analysis result showed three main factors associated with time management which can be classified as time planning, time attitudes and time wasting. The mechanisms mediating the increased production of monocytes and their influence on ICH remain to be elucidated. We did a randomised, double-blind, placebo-controlled, multicentre trial at ten hospitals in Hubei, China. First Case of 2019 Novel Coronavirus in the United States. More Information. By 10 March 2020, 4296 persons world-wide had died from COVID-19 infection. 1 The overall case-fatality rate is very country-specific for COVID-19 infection and depending on the phase of the epidemic, testing, registration, demography, healthcare capacity and governmental decisions. An oral ASO to lower LDL. We did a randomised, double-blind, placebo-controlled, multicentre trial at ten hospitals in Hubei, China. Aiming to contain the spread of the virus, leaders of many countries restrained social movement, targeting to flatten the curve of contamination with social distancing. 2020;8(4):128. developed an antisense oligonucleotide (ASO) that can be delivered orally, is taken up by the liver, and targets PCSK9, which regulates the LDL receptor.Subcutaneous administration of the ASO showed high potency in mice overexpressing … The gut microbiome has a measurable impact on the brain, influencing stress, anxiety, depressive symptoms and social behaviour. The COVID-19 pandemic and human fertility. Google Scholar 84. 2020;66(8):1027–9. 1 The overall case-fatality rate is very country-specific for COVID-19 infection and depending on the phase of the epidemic, testing, registration, demography, healthcare capacity and governmental decisions. 1 IntroductionAs of 30th January 2020, the outbreak of the novel coronavirus disease, latterly called COVID-19, was declared a Public Health Emergency (World Health Organization, 2020b) and on the 11th of March 2020, COVID-19 was characterized as a pandemic (World Health Organization, 2020d). The number of people suffering from inflammatory bowel diseases, especially Crohn's disease, has increased remarkably. 1 The overall case-fatality rate is very country-specific for COVID-19 infection and depending on the phase of the epidemic, testing, registration, demography, healthcare capacity and governmental decisions. Aassve A, Cavalli N, Mencarini L, Plach S, Livi BM. In this review, we critically appraise the current pharmacological, preclinical and clinical data of azithromycin for treating COVID-19. 2020;110(11):1081–5. Infection with SARs-COV-2 displays increasing fatality with age and underlying co-morbidity, in particular, with markers of the metabolic syndrome and diabetes, which seems to be associated with a “cytokine storm” and an altered immune response. Aiming to contain the spread of the virus, leaders of many countries restrained social movement, targeting to flatten the curve of contamination with social distancing. Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. (2020) Impact of COVID-19 on lifestyle-related behaviours-a cross-sectional audit of responses from nine hundred and ninety-five participants from India. Immune effector cell (IEC) therapies offer durable and sustained remissions in significant numbers of patients with hematological cancers. 2020 24. ... Ranjan, P, Singh, V et al. Modeling suggests shielding is an effective strategy to protect individuals and control the impact of SARS-CoV-2 . Yoon SH, Kang JM, Ahn JG. 1093/gerona/glaa099. 2020;24(14):7804–15. 1093/gerona/glaa099. Here, Shi et al. Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis. S Afr Med J. The Impact of Time Management on Students' Academic Achievement. Google Scholar The gut microbiome has a measurable impact on the brain, influencing stress, anxiety, depressive symptoms and social behaviour. CAS PubMed PubMed Central Google Scholar 91. Several reports, papers, guidelines, and suggestions have been released on how this infection could be transmitted through dental services and what should be done. 2020 24. The Impact of Time Management on Students' Academic Achievement. S Afr Med J. We did a randomised, double-blind, placebo-controlled, multicentre trial at ten hospitals in Hubei, China. Aassve A, Cavalli N, Mencarini L, Plach S, Livi BM. 2020; 12:1–22. Infection with SARs-COV-2 displays increasing fatality with age and underlying co-morbidity, in particular, with markers of the metabolic syndrome and diabetes, which seems to be associated with a “cytokine storm” and an altered immune response. Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H. et al. Yang S, Cao P, Du P, Wu Z, Zhuang Z, Yang L, et al. Potential Interventions for Novel Coronavirus in China: A Systemic Review. ... Ranjan, P, Singh, V et al. In patients with intracerebral hemorrhage (ICH), circulating myeloid cells increase and peripheral immune cells infiltrate into the brain parenchyma. 2017:9 22. J Med Virol. Here, Shi et al. Eur J Sport Sci. These lockdowns have the potential to impact associated levels of physical activity and sedentary behaviour. Among several potential transmission sources in the spreading of the COVID-19, dental services have received a high volume of attention. CAS PubMed PubMed Central Google Scholar 91. Curr Med Sci 2020;:1–6. The factor analysis result showed three main factors associated with time management which can be classified as time planning, time attitudes and time wasting. Clinical outcomes of 201 neonates born to mothers with COVID-19: a systematic review. 2020 24. Here, Gennemark et al. The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer. Cancer Treat Rev 2016 ;45: 139 - 162 . Alzheimer’s disease (AD) and treatment of the brain in aging require the development of new biologic drugs, such as recombinant proteins or gene therapies. An oral ASO to lower LDL. N Engl J Med. 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